SCHEMBL28670367

SCHEMBL28670367

O=S(=O)([O-])CC(O)CBr.[Na+]

nearest known ligand 0.38

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 1/20 0.34
CA2 known ✓ P00918 1/20 0.34
CA4 known ✓ P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium Ion SCHEMBL28678573 0.95 CA1 (0.34) CA1CA2CA4CA7CA9
Potassium Ion SCHEMBL28579061 0.95 CA1 (0.34) CA1CA2CA4CA7CA9
SCHEMBL1308988 0.77 ALDH1A1 (0.47) MEN1ALDH1A1TSHRKMT2ATP53
SCHEMBL26976755 0.77 ALDH1A1 (0.47) MEN1ALDH1A1TSHRKMT2ATP53
SCHEMBL23530434 0.75 CA1 (0.36) CA1CA2CA9MEN1ALDH1A1
SCHEMBL4430233 0.75 ENPEP (0.40) MEN1ALDH1A1TSHRKMT2ATP53
SCHEMBL1323117 0.75 GABRR1 (0.37) MEN1ALDH1A1TSHRKMT2ATP53
SCHEMBL28654536 0.75 MEN1 (0.32) MEN1ALDH1A1TSHRKMT2ATP53
SCHEMBL272976 0.75 CA1 (0.36) CA1CA2CA9MEN1ALDH1A1
SCHEMBL491192 0.75 TSHR (0.32) MEN1ALDH1A1TSHRKMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164485-A Negative charge-rich complexing reagent, preparation method thereof and application thereof in negative electrolyte of all-iron flow battery 华中科技大学 2023-12-05 CN claimed
CN-113769592-B Quaternized modified polyarylether membrane material and preparation method and application thereof 吉林大学 2022-06-24 CN claimed
CN-113769592-A Quaternized modified polyarylether membrane material and preparation method and application thereof 吉林大学 2021-12-10 CN claimed
CN-101912745-A Sulfamic acid amphoteric surfactant and synthesis method thereof CHAOHUA REN 2010-12-15 CN claimed
CN-119775173-A Method for preparing 2, 3-dibromopropane sulfonic acid 合肥立方制药股份有限公司 2025-04-08 CN disclosed
CN-117164485-B Negative charge-rich complexing reagent, preparation method thereof and application thereof in negative electrolyte of all-iron flow battery 华中科技大学 2024-02-09 CN disclosed
CN-117164485-A Negative charge-rich complexing reagent, preparation method thereof and application thereof in negative electrolyte of all-iron flow battery 华中科技大学 2023-12-05 CN disclosed
CN-113769592-B Quaternized modified polyarylether membrane material and preparation method and application thereof 吉林大学 2022-06-24 CN disclosed
CN-113769592-A Quaternized modified polyarylether membrane material and preparation method and application thereof 吉林大学 2021-12-10 CN disclosed
CN-109401741-B Method for reducing adsorption loss of oil displacement fluid 中国石油化工股份有限公司 2021-11-30 CN disclosed
CN-109401744-B Oil displacement fluid containing adsorption inhibitor and application thereof in tertiary oil recovery 中国石油化工股份有限公司 2021-11-30 CN disclosed
CN-109403932-B Oil displacement method for reducing adsorption loss 中国石油化工股份有限公司 2021-11-30 CN disclosed