SCHEMBL2867870

SCHEMBL2867870

c1ccc(C[SiH]Cc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.50
TSHR P16473 4/20 0.45
ALDH1A1 P00352 3/20 0.45
IDO1 P14902 3/20 0.45
LOXL2 Q9Y4K0 2/20 0.45
TP53 P04637 1/20 0.45
TRPA1 O75762 1/20 0.45
MAOB P27338 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
THRB P10828 1/20 0.39
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043268 0.83 TP53 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL11796645 0.75
SCHEMBL6185704 0.69
SCHEMBL17386441 0.69 ALDH1A1 (0.52) CALM1TSHRALDH1A1IDO1LOXL2
Diphenylmethane SCHEMBL4361124 0.67 CALM1 (1.00) CALM1TSHRALDH1A1IDO1LOXL2
Diphenylmethane SCHEMBL14763944 0.67 CALM1 (1.00) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL9741303 0.67 ALDH1A1 (0.69) CALM1ALDH1A1LOXL2MAOBHPGD
SCHEMBL62125 0.67 ALDH1A1 (0.69) CALM1ALDH1A1LOXL2MAOBHPGD
Diphenylmethane SCHEMBL1303 0.67 CALM1 (1.00) CALM1TSHRALDH1A1IDO1LOXL2
Diphenylmethane SCHEMBL3792579 0.67 CALM1 (1.00) CALM1TSHRALDH1A1IDO1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116999396-A Modular compositions for removal of soluble biomolecules and related methods 纳米提克斯有限责任公司 2023-11-07 CN disclosed
CN-107406476-B Mononuclear iron complex and organic synthesis reaction using same 国立大学法人九州大学 2021-07-27 CN disclosed
EP-3118205-B1 MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP disclosed
EP-3269724-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP disclosed
US-10363551-B2 Mononuclear iron complex and organic synthesis reaction using same KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2019-07-30 US disclosed
EP-2963047-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2018-11-14 EP disclosed
EP-2963046-B1 MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2018-10-17 EP disclosed
US-20180243732-A1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-08-30 US disclosed
US-9884316-B2 Mononuclear ruthenium complex and organic synthesis reaction using same KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-02-06 US disclosed
EP-3269724-A1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME Kyushu University National University Corporation (JP) 2018-01-17 EP disclosed
EP-0584646-A2 Process for producing styrenic polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-03-02 EP disclosed
EP-0566068-A2 Process for purification of styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-10-20 EP disclosed
EP-0554574-A1 Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-08-11 EP disclosed
EP-0543022-A1 PROCESS FOR PRODUCING STYRENIC POLYMER AND CATALYST THEREFOR IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-05-26 EP disclosed
EP-0535582-A1 Process for producing styrenic polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-04-07 EP disclosed
EP-0505890-A2 Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0505973-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0497207-A2 Process for purification of styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-08-05 EP disclosed
EP-0492282-A1 Process for producing a styrene polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180243732-A1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME TFRC, IDO1, H1-0 CALM1 3389/4885TSHR 726/4885ALDH1A1 2768/4885
US-10363551-B2 Mononuclear iron complex and organic synthesis reaction using same TFRC, IDO1, H1-0 CALM1 3389/4885TSHR 726/4885ALDH1A1 2768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.