Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16934944 | 0.84 | ALDH1A1 (0.50) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1475915 | 0.83 | LDHA (0.53) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6984490 | 0.80 | MEN1 (0.51) | SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15262094 | 0.80 | SLC6A3 (0.43) | MAPTPPARGPPARA | |
| SCHEMBL7330916 | 0.78 | MAPT (0.53) | CA1CA2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27504804 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL11402555 | 0.77 | TAS1R3 (0.65) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16728392 | 0.77 | TAS1R3 (0.65) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9423676 | 0.76 | LDHA (0.64) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL903865 | 0.75 | NPC1 (0.46) | NPC1RAB9APPARGPPARAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-113999232-A | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2022-02-01 | — | — | CN | disclosed |