Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15154524 | 0.84 | MEN1 (0.58) | KMT2AMEN1ALDH1A1EGFRGAA | |
| SCHEMBL2443786 | 0.84 | EGLN1 (0.60) | KMT2AMEN1ALDH1A1MAP3K5L3MBTL1 | |
| SCHEMBL28678807 | 0.83 | MEN1 (0.51) | KMT2AMEN1ALDH1A1L3MBTL1POLB | |
| SCHEMBL889415 | 0.82 | EGFR (0.51) | KMT2AMEN1ALDH1A1MAP3K5EGFR | |
| SCHEMBL2381250 | 0.82 | EGLN1 (0.61) | KMT2AMEN1NPC1RAB9AEGLN1 | |
| SCHEMBL29463790 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1MAP3K5L3MBTL1 | |
| SCHEMBL17713228 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1MAP3K5L3MBTL1 | |
| SCHEMBL2382478 | 0.81 | L3MBTL1 (0.51) | KMT2AMEN1ALDH1A1MAP3K5L3MBTL1 | |
| SCHEMBL2382482 | 0.81 | L3MBTL1 (0.51) | KMT2AMEN1ALDH1A1MAP3K5L3MBTL1 | |
| SCHEMBL7753691 | 0.81 | AGTR1 (0.42) | KMT2AMEN1ALDH1A1MAP3K5EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073639-B1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| US-6077851-A | USED FOR TREATMENT OF DISEASES RESULTING FROM AUTOIMMUNITY SUCH AS MULTIPLE SCLEROSIS, INSULIN-DEPENDENT DIABETES MELLITUS, SYSTEMIC LUPUS ERYTHEMATOSUS, RHEUMATOID ARTHRITIS, INFAMMATORY BOWEL DISEASE AND PSORIASIS; LAQUINIMOD AS NEW CHEMICAL ENTITY | ACTIVE BIOTECH AB (SE) | 2000-06-20 | — | — | US | disclosed |