SCHEMBL28678998

SCHEMBL28678998

CCCCC(CC)COc1cccc(O)c1-c1nc(-c2ccc(OC)cc2)nc(-c2ccccc2O)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.38
KMT2A Q03164 8/20 0.38
MEN1 O00255 7/20 0.38
POLB P06746 3/20 0.38
ATM Q13315 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAPT P10636 7/20 0.36
HPGD P15428 2/20 0.36
TSHR P16473 2/20 0.36
KDM4E B2RXH2 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ALOX15 P16050 2/20 0.36
ALOX12 P18054 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
RXFP1 Q9HBX9 2/20 0.36
TP53 P04637 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29354615 0.90 LMNA (0.36) LMNAKMT2AMEN1POLBATM
SCHEMBL7057519 0.88 LMNA (0.41) LMNAKMT2AMEN1POLBATM
SCHEMBL4554162 0.87 TDP1 (0.41) LMNAKMT2AMEN1TDP1MAPT
Bemotrizinol SCHEMBL29360093 0.81 TDP1 (0.43) LMNAKMT2AMEN1TDP1MAPT
Bemotrizinol SCHEMBL29350308 0.81 TDP1 (0.43) LMNAKMT2AMEN1TDP1MAPT
Bemotrizinol SCHEMBL77320 0.81 TDP1 (0.43) LMNAKMT2AMEN1TDP1MAPT
SCHEMBL10195000 0.81 TDP1 (0.43) LMNAKMT2AMEN1TDP1MAPT
SCHEMBL12877715 0.81 TDP1 (0.39) LMNAKMT2AMEN1POLBTDP1
Bemotrizinol SCHEMBL26987980 0.81 TDP1 (0.39) LMNAKMT2AMEN1TDP1MAPT
Bemotrizinol SCHEMBL4563326 0.81 LMNA (0.36) LMNAKMT2AMEN1POLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117460975-A Polarizing plate and organic EL display device 日东电工株式会社 2024-01-26 CN disclosed
CN-113969123-A Adhesive composition, adhesive sheet, polarizing plate with adhesive, and image display device 日东电工株式会社 2022-01-25 CN disclosed
CN-113969118-A Adhesive sheet, adhesive-attached polarizing plate, image display device, and method for manufacturing same 日东电工株式会社 2022-01-25 CN disclosed