Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25736837 | 0.85 | MAPT (0.44) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL28681187 | 0.81 | GABRG2 (0.41) | MAPTALDH1A1GABRG2GABRB3GABRA5 | |
| SCHEMBL28808278 | 0.79 | MAPT (0.44) | MAPTALDH1A1LMNAGABRG2GABRB3 | |
| SCHEMBL29780834 | 0.79 | MAPT (0.44) | MAPTALDH1A1LMNAGABRG2GABRB3 | |
| SCHEMBL2340371 | 0.77 | L3MBTL1 (0.45) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL5446082 | 0.76 | MAPT (0.46) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29540947 | 0.76 | MAPT (0.46) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL15208411 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL840482 | 0.74 | MAPT (0.47) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL28808282 | 0.74 | CCR2 (0.47) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943259-A | Amino acid derivative, preparation method and application thereof | 西安禾渼生物医药有限公司 | 2022-01-18 | — | — | CN | disclosed |