Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | DHODH | Q02127 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673422 | 0.90 | MEN1 (0.59) | KDM4EALDH1A1KMT2AMEN1APOBEC3A | |
| SCHEMBL28931754 | 0.89 | MEN1 (0.59) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28681436 | 0.88 | STAT3 (0.61) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28683183 | 0.87 | CHEK1 (0.58) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28695985 | 0.86 | STAT3 (0.55) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28699093 | 0.86 | CTDSP1 (0.62) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28673399 | 0.85 | MEN1 (0.58) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28699068 | 0.85 | STAT3 (0.54) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28690124 | 0.84 | ALDH1A1 (0.58) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28679409 | 0.83 | STAT3 (0.54) | KDM4EMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |