Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.48 |
| ▸ | LPL | P06858 | 6/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534422 | 0.84 | ANPEP (0.42) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28623123 | 0.79 | CA1 (0.46) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28623122 | 0.79 | CA1 (0.46) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20905534 | 0.78 | LIPG (0.46) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL12675946 | 0.76 | SLC7A5 (0.53) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16501554 | 0.74 | ESR2 (0.52) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17894215 | 0.74 | ESR2 (0.56) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5336869 | 0.74 | F11 (0.56) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7903372 | 0.74 | F11 (0.50) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9280171 | 0.73 | CTSK (0.55) | LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |