Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 4/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24730390 | 0.84 | PTPRC (0.59) | S100A4BCL2MCL1MAOAPTPRC | |
| SCHEMBL571761 | 0.83 | MEN1 (0.63) | S100A4BCL2MCL1MAOAPTPRC | |
| SCHEMBL10023270 | 0.82 | AHR (0.44) | CYP3A4AHRGABRA1GABRB1GABRA2 | |
| SCHEMBL9354025 | 0.81 | CA1 (0.40) | S100A4BCL2MCL1ESR1MAOA | |
| SCHEMBL16682965 | 0.81 | BCHE (0.53) | S100A4BCL2MCL1ESR1MAOA | |
| SCHEMBL23958837 | 0.81 | S100A4 (0.36) | S100A4BCL2MCL1ESR1MAOA | |
| SCHEMBL23968936 | 0.81 | BCL2 (0.54) | S100A4BCL2MCL1ESR1MAOA | |
| SCHEMBL17430717 | 0.77 | LMNA (0.39) | S100A4BCL2MCL1CYP1A2ALDH1A1 | |
| SCHEMBL15131710 | 0.77 | BCHE (0.55) | S100A4BCL2MCL1ESR1MAOA | |
| SCHEMBL13030544 | 0.76 | PTPRC (0.55) | S100A4BCL2MCL1MAOAPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117548-B | Spirofluorene compound, application thereof, thermal activation delayed fluorescence material and organic electroluminescent device using spirofluorene compound | 北京鼎材科技有限公司 | 2022-01-28 | — | — | CN | disclosed |