SCHEMBL23958837

SCHEMBL23958837

O=C1c2cc(Br)c(I)cc2-c2cc(I)c(Br)cc21

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.36
CYP1A2 P05177 1/20 0.35
BCL2 P10415 3/20 0.34
MCL1 Q07820 2/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
PTPRC P08575 1/20 0.31
ESR1 P03372 1/20 0.31
MAOA P21397 1/20 0.31
UGT1A1 P22309 1/20 0.31
MAOB P27338 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30494516 0.95 S100A4 (0.41) S100A4CYP1A2BCL2MCL1CA1
SCHEMBL22233097 0.88 PTPRC (0.50) S100A4CYP1A2BCL2MCL1PTPRC
SCHEMBL28680807 0.81 S100A4 (0.43) S100A4CYP1A2BCL2MCL1PTPRC
SCHEMBL734024 0.76 ALOX15 (0.39)
SCHEMBL735361 0.74 ELANE (0.36)
SCHEMBL16193369 0.73
SCHEMBL733492 0.71 APEX1 (0.33) CA1CA2CA9
SCHEMBL9354025 0.70 CA1 (0.40) S100A4CYP1A2BCL2MCL1CA1
SCHEMBL23968936 0.70 BCL2 (0.54) S100A4CYP1A2BCL2MCL1ESR1
SCHEMBL16682965 0.70 BCHE (0.53) S100A4CYP1A2BCL2MCL1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11322694-B2 Electroluminescent material, method for manufacturing same, and light emitting device WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-05-03 US disclosed
US-20210336152-A1 ELECTROLUMINESCENT MATERIAL, METHOD FOR MANUFACTURING SAME, AND LIGHT EMITTING DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11322694-B2 Electroluminescent material, method for manufacturing same, and light emitting device GPR17, CALCR, TAAR1 S100A4 2471/4885CYP1A2 2184/4885BCL2 3739/4885
US-20210336152-A1 ELECTROLUMINESCENT MATERIAL, METHOD FOR MANUFACTURING SAME, AND LIGHT EMITTING DEVICE GPR17, CALCR, TAAR1 S100A4 2471/4885CYP1A2 2184/4885BCL2 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.