SCHEMBL23968936

SCHEMBL23968936

O=C1c2cc(O)c(Br)cc2-c2cc(Br)c(O)cc21

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 7/20 0.54
MCL1 Q07820 7/20 0.54
ESR1 P03372 1/20 0.41
MAOA P21397 1/20 0.41
UGT1A1 P22309 1/20 0.41
MAOB P27338 1/20 0.41
ESR2 Q92731 1/20 0.41
PKLR P30613 1/20 0.37
ALOX15 P16050 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37
S100A4 P26447 1/20 0.36
HSP90AA1 P07900 1/20 0.35
CYP1A2 P05177 1/20 0.35
TTR P02766 1/20 0.34
GPR35 Q9HC97 2/20 0.34
EP300 Q09472 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6629644 0.88 BCL2 (0.67) BCL2MCL1MAOAPKLRS100A4
SCHEMBL11359105 0.87 BCL2 (0.72) BCL2MCL1ESR1MAOAUGT1A1
SCHEMBL7980260 0.81 BCL2 (0.70) BCL2MCL1ESR1MAOAUGT1A1
SCHEMBL28680807 0.81 S100A4 (0.43) BCL2MCL1ESR1MAOAUGT1A1
SCHEMBL8821657 0.78 BCL2 (0.74) BCL2MCL1ESR1MAOAUGT1A1
SCHEMBL13672134 0.73 ALOX15 (0.50) BCL2MCL1ESR1ESR2ALOX15
SCHEMBL48448 0.71 ALOX15 (0.53) ALOX15GABRA1GABRB1GABRA2GABRB2
SCHEMBL9354025 0.70 CA1 (0.40) BCL2MCL1ESR1MAOAUGT1A1
SCHEMBL23958837 0.70 S100A4 (0.36) BCL2MCL1ESR1MAOAUGT1A1
SCHEMBL28046162 0.70 MCL1 (0.50) BCL2MCL1ESR1MAOAUGT1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 BCL2 2488/4885MCL1 2072/4885ESR1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.