Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.71 |
| ▸ | HTR1D | P28221 | 4/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.61 |
| ▸ | ICMT | O60725 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | HTR1B | P28222 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR5A | P47898 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717632 | 0.93 | MPO (0.70) | MPOSLC6A4HTR1DHTR2AMTNR1A | |
| SCHEMBL10344769 | 0.89 | MTNR1A (0.65) | MPOSLC6A4HTR1DHTR2AMTNR1A | |
| SCHEMBL10344751 | 0.89 | MTNR1A (0.61) | MPOSLC6A4HTR1DHTR2AMTNR1A | |
| SCHEMBL28681119 | 0.89 | HTR2A (0.64) | MPOSLC6A4HTR1DHTR2AMTNR1A | |
| SCHEMBL1395838 | 0.84 | ICMT (0.79) | MPOHTR1DHTR2AMTNR1AMTNR1B | |
| SCHEMBL3695233 | 0.83 | MPO (1.00) | MPOSLC6A4HTR2AMTNR1AMTNR1B | |
| SCHEMBL28673230 | 0.83 | MPO (0.71) | MPOSLC6A4HTR1DHTR2AMEN1 | |
| SCHEMBL10363555 | 0.83 | HTR2A (0.60) | MPOSLC6A4HTR1DHTR2AMTNR1A | |
| Hydrochloric Acid SCHEMBL4978512 | 0.82 | ICMT (0.77) | MPOHTR1DHTR2AMTNR1AMTNR1B | |
| SCHEMBL31036156 | 0.82 | HPGD (0.69) | MPOSLC6A4HTR1DHTR2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943244-A | Sulfur-containing gamma, gamma-diindolyl butyramide compound prepared by double-functionalization reaction | 温州大学 | 2022-01-18 | — | — | CN | disclosed |