SCHEMBL28680993

SCHEMBL28680993

CC(C)(c1ccc(C(Cc2ccc(O)cc2)c2ccc(O)cc2)cc1)c1ccc(O)c(F)c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.43
ESR2 Q92731 11/20 0.43
CYP3A4 P08684 2/20 0.42
ESRRG P62508 2/20 0.42
AR P10275 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
HTR6 P50406 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 1/20 0.41
RORC P51449 1/20 0.38
KLF10 Q13118 1/20 0.38
CYP17A1 P05093 1/20 0.38
SHBG P04278 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30320268 1.00 ESR1 (0.43) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL30375004 0.90 SHBG (0.40) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL15475852 0.86 ESR1 (0.57) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL3354777 0.86 ESR1 (0.57) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL30375009 0.85 ESR1 (0.48) ESR1ESR2ESRRGARRORC
SCHEMBL30375052 0.84 ESRRG (0.38) ESR1ESR2CYP3A4ESRRGTSHR
Bisphenol A SCHEMBL6607352 0.83 ESR1 (0.61) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL30625965 0.83 ESR1 (0.61) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL16565722 0.83 ESR1 (0.61) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL30374729 0.83 ESR1 (0.41) ESR1ESR2ESRRGARRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-116209725-A Reversible thermochromic composition and reversible thermochromic microcapsule pigment having the same encapsulated therein 百乐墨水株式会社 2023-06-02 CN disclosed
CN-116113548-A Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing same 百乐墨水株式会社 2023-05-12 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed
CN-113785023-A Water-based ink composition for reversible thermal discoloration writing instrument, refill containing the same, and water-based ballpoint pen 株式会社百乐 2021-12-10 CN disclosed