SCHEMBL30375004

SCHEMBL30375004

CC(C)(c1ccc(C(Cc2ccc(O)c(F)c2)c2ccc(O)c(F)c2)cc1)c1ccc(O)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.40
ESRRG P62508 1/20 0.39
RORC P51449 1/20 0.38
ESR1 P03372 4/20 0.38
KLF10 Q13118 1/20 0.38
CYP17A1 P05093 1/20 0.38
PDE4A P27815 1/20 0.35
GRIN2B Q13224 5/20 0.33
ALOX15 P16050 4/20 0.33
ALOX12 P18054 4/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 2/20 0.33
CYP3A4 P08684 2/20 0.33
HPGD P15428 2/20 0.33
MAPK1 P28482 2/20 0.33
RECQL P46063 2/20 0.33
KMT2A Q03164 2/20 0.33
HIF1A Q16665 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30375009 0.90 ESR1 (0.48) SHBGESRRGRORCESR1KLF10
SCHEMBL30320268 0.90 ESR1 (0.43) SHBGESRRGRORCESR1KLF10
SCHEMBL28680993 0.90 ESR1 (0.43) SHBGESRRGRORCESR1KLF10
SCHEMBL30375052 0.89 ESRRG (0.38) SHBGESRRGRORCESR1KLF10
SCHEMBL27002596 0.83 ESR1 (0.41) SHBGESRRGRORCESR1KLF10
SCHEMBL30374729 0.83 ESR1 (0.41) SHBGESRRGRORCESR1KLF10
SCHEMBL30320269 0.81 ESR1 (0.56) ESRRGRORCESR1KLF10ALOX15
SCHEMBL30375183 0.80 RORC (0.37) ESRRGRORCESR1KLF10PDE4A
SCHEMBL30374761 0.79 CA2 (0.40) RORCESR1KLF10ALOX15ALOX12
SCHEMBL30374574 0.79 RORC (0.38) RORCESR1KLF10PDE4AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed