Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895992 | 0.80 | NOTUM (0.49) | NOTUMMAPTRAB9AALDH1A1 | |
| SCHEMBL12804219 | 0.79 | MAPT (0.42) | TDP1MAPTRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL1040317 | 0.79 | NOTUM (0.34) | TDP1NOTUMMAPTRAB9AALDH1A1 | |
| SCHEMBL17626275 | 0.75 | NOTUM (0.47) | NOTUMMAPTRAB9AMGLL | |
| SCHEMBL7160362 | 0.75 | F2 (0.35) | TDP1NOTUMMAPTRAB9AL3MBTL1 | |
| SCHEMBL7160454 | 0.74 | ALKBH5 (0.39) | NOTUM | |
| SCHEMBL28698714 | 0.70 | TDP1 (0.41) | TDP1KIF11NOTUMCYP11B2MAPT | |
| SCHEMBL5983395 | 0.70 | KDM4E (0.44) | ALDH1A1HIF1A | |
| SCHEMBL5445153 | 0.68 | TDP1 (0.35) | TDP1KIF11NOTUMGSK3AGSK3B | |
| SCHEMBL709619 | 0.68 | LMNA (0.58) | TDP1NOTUMCYP11B2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072000-A | Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2022-02-18 | — | — | CN | disclosed |