Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428166 | 0.93 | MAPT (0.54) | MAPTCA12CA9MAPK1TP53 | |
| SCHEMBL28699030 | 0.93 | MAPT (0.54) | MAPTCA12CA9MAPK1TP53 | |
| SCHEMBL28688249 | 0.79 | ALDH1A1 (0.58) | MAPTCA12CA9TP53ALDH1A1 | |
| SCHEMBL29428151 | 0.77 | MAPT (0.54) | MAPTTP53BACE1ALDH1A1KDM4E | |
| SCHEMBL28685040 | 0.77 | MAPT (0.54) | MAPTTP53BACE1ALDH1A1KDM4E | |
| SCHEMBL6243745 | 0.76 | MAPT (0.60) | MAPTTSHRMAPK1TP53BACE1 | |
| SCHEMBL28683072 | 0.74 | MEN1 (0.58) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL29428168 | 0.74 | SETD7 (0.64) | MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28692022 | 0.74 | SETD7 (0.64) | MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL10085009 | 0.73 | KDM4E (0.68) | MAPTALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776434-B | 3-benzyl-6-acylamino-2, 4- (1H,3H) -quinazoline diketone derivative and synthesis method and application thereof | 中南大学 | 2022-01-28 | — | — | CN | disclosed |