Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CTSA | P10619 | 3/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566940 | 0.86 | AR (0.51) | ARPOLBGAACTSAIMPDH2 | |
| SCHEMBL7181751 | 0.85 | AR (0.50) | ARPOLBGAACTSAIMPDH2 | |
| Water SCHEMBL28136778 | 0.82 | CA1 (0.55) | ARGAAFABP3FABP4FABP5 | |
| SCHEMBL3255414 | 0.81 | ALDH1A1 (0.47) | ARPOLBCTSASMN1; SMN2ABL1 | |
| SCHEMBL19820790 | 0.81 | POLB (0.63) | ARPOLBGAAIMPDH2IMPDH1 | |
| SCHEMBL355567 | 0.80 | CA1 (0.57) | ARGAAFABP3FABP4FABP5 | |
| SCHEMBL18411452 | 0.80 | TSHR (0.46) | SMN1; SMN2 | |
| SCHEMBL8596052 | 0.79 | IMPDH2 (0.53) | ARPOLBGAAIMPDH2IMPDH1 | |
| SCHEMBL7575609 | 0.79 | IMPDH2 (0.53) | ARIMPDH2IMPDH1MAOAMAOB | |
| SCHEMBL28641928 | 0.79 | AR (0.49) | ARPOLBGAACTSAIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602770-B | Novel biphenyl compound or salt thereof | 大鹏药品工业株式会社 | 2022-02-08 | — | — | CN | disclosed |