Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715396 | 0.81 | LOXL2 (0.55) | LOXL2KCNH2KCNJ1MEN1KMT2A | |
| SCHEMBL10076419 | 0.80 | ADRA2B (0.69) | SLC6A4CRHBPCRHR2PYCR1KCNH2 | |
| SCHEMBL9969472 | 0.79 | CRHBP (0.46) | CRHBPCRHR2LOXL2PYCR1KCNH2 | |
| SCHEMBL465658 | 0.79 | LOXL2 (0.48) | CRHBPCRHR2LOXL2PYCR1KCNH2 | |
| SCHEMBL20431221 | 0.78 | LOXL2 (0.52) | CRHBPCRHR2LOXL2KCNH2KCNJ1 | |
| SCHEMBL8986807 | 0.78 | LOXL2 (0.62) | SLC6A4LOXL2KCNH2KCNJ1MEN1 | |
| SCHEMBL1625876 | 0.78 | MEN1 (0.56) | LOXL2KCNH2KCNJ1MEN1KMT2A | |
| SCHEMBL2325845 | 0.78 | LMNA (0.53) | LOXL2KCNH2KCNJ1MEN1KMT2A | |
| SCHEMBL29963038 | 0.78 | LOXL2 (0.52) | CRHBPCRHR2LOXL2PYCR1KCNH2 | |
| SCHEMBL395680 | 0.78 | LOXL2 (0.52) | CRHBPCRHR2LOXL2KCNH2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108611-A | Multi-source multi-phase catalytic advanced oxidation coupling reaction device and method for efficient treatment of industrial wastewater | 江苏省环境工程技术有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | disclosed |