Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 8/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29509339 | 1.00 | LMNA (0.50) | LMNATP53PIM1CSNK2A2CSNK2B | |
| SCHEMBL22323745 | 0.86 | LRRK2 (0.41) | LMNATP53ALDH1A1KDM4EHPGD | |
| SCHEMBL29509324 | 0.86 | LRRK2 (0.41) | LMNATP53ALDH1A1KDM4EHPGD | |
| SCHEMBL20563607 | 0.84 | PIM1 (0.56) | LMNATP53PIM1CSNK2A2CSNK2B | |
| SCHEMBL11739995 | 0.80 | PIM1 (0.57) | LMNATP53PIM1CSNK2A2CSNK2B | |
| SCHEMBL4766674 | 0.76 | PIM1 (0.55) | LMNATP53PIM1CSNK2A2CSNK2B | |
| SCHEMBL19147152 | 0.73 | GPR35 (0.41) | MCL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16723484 | 0.72 | GPR35 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5584443 | 0.71 | LMNA (0.48) | LMNATP53PIM1CSNK2A2CSNK2B | |
| SCHEMBL1390620 | 0.71 | LMNA (0.43) | LMNATP53ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007614-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-02-01 | — | — | CN | disclosed |