Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723484 | 0.84 | GPR35 (0.41) | GPR35MAOBALDH1A1TSHRPPARG | |
| SCHEMBL9058086 | 0.82 | MCL1 (0.53) | GPR35MAOBALDH1A1MCL1TSHR | |
| SCHEMBL16722825 | 0.80 | GPR35 (0.39) | GPR35MAOBALDH1A1TSHRPPARG | |
| SCHEMBL21457027 | 0.78 | MAOA (0.44) | MAOB | |
| SCHEMBL29625894 | 0.76 | MCL1 (0.55) | MAOBALDH1A1MCL1 | |
| SCHEMBL19147577 | 0.74 | MCL1 (0.67) | ALDH1A1MCL1PPARG | |
| SCHEMBL29509339 | 0.73 | LMNA (0.50) | ALDH1A1MCL1SMN1; SMN2 | |
| SCHEMBL28686553 | 0.73 | LMNA (0.50) | ALDH1A1MCL1SMN1; SMN2 | |
| SCHEMBL29625900 | 0.72 | KDM4E (0.50) | GPR35MAOBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28635360 | 0.72 | KDM4E (0.50) | GPR35MAOBALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017122722-A1 | BIHETEROCYCLIC COMPOUND | 大日本住友製薬株式会社 | 2017-07-20 | — | — | WO | disclosed |