SCHEMBL17372419

SCHEMBL17372419

CSc1nc(NC(=O)NC(=O)[C@@H](N)[C@@H](C)O)c2nc[nH]c2n1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2D6 P10635 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17372415 1.00 CYP1A2 (0.30) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL29278769 0.91 SPHK1 (0.32) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL25244196 0.84 CYP1A2 (0.31) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL28960555 0.83 MEN1 (0.38) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL17372418 0.83 CYP1A2 (0.46) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL29638102 0.83 CYP1A2 (0.46) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL17372558 0.81 NPC1 (0.35) —
SCHEMBL17372562 0.81 NPC1 (0.35) —
SCHEMBL17372402 0.79 CYP1A2 (0.34) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL546925 0.78 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106695-A1 TARGETED NANOPARTICLES ENCAPSULATING WATER-SOLUBLE THERAPEUTICS, METHODS OF PRODUCTION, AND USE OPTIMEOS LIFE SCIENCES, INC. (US) 2026-05-21 — — WO disclosed
WO-2026098357-A1 FREEZE-DRIED NUCLEIC ACID-LOADED LIPID NANOPARTICLE AND RECONSTITUTION METHOD THEREOF KUDO BIOTECHNOLOGY, INC. (US) 2026-05-15 — — WO disclosed
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS PFIZER INC. (US) 2026-05-14 — — US disclosed
WO-2026088119-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 — — WO disclosed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 — — US disclosed
EP-4720094-A1 MUTATED FRAGMENT OF VZV GLYCOPROTEIN E Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-08 — — EP disclosed
US-12594242-B2 Lipid compounds and lipid nanoparticle compositions Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-07 — — US disclosed
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 — — US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 — — US disclosed
US-20260061042-A1 POLYNUCLEOTIDE COMPOSITIONS AND USES THEREOF PFIZER (US) 2026-03-05 — — US disclosed
WO-2017066781-A1 MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066782-A1 HYDROPHOBIC MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066791-A1 SUGAR SUBSTITUTED MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066789-A1 MRNA CAP ANALOGS WITH MODIFIED SUGAR MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066797-A1 TRINUCLEOTIDE MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017049275-A2 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNA THERAPEUTICS, INC. (US) 2017-03-23 — — WO disclosed
WO-2017049286-A1 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER MODERNA THERAPEUTICS, INC. (US) 2017-03-23 — — WO disclosed
WO-2017049245-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-03-23 — — WO disclosed
WO-2015196130-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 — — WO disclosed
WO-2015196118-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION RNGTT, RNMT, UPF1 CYP1A2 4691/4885CYP3A4 4592/4885CYP2D6 4469/4885
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS SARS1, CD14, PYCARD CYP1A2 1814/4885CYP3A4 2197/4885CYP2D6 3089/4885
US-12594242-B2 Lipid compounds and lipid nanoparticle compositions NPC1, NPC1L1, PLIN3 CYP1A2 2005/4885CYP3A4 2426/4885CYP2D6 1033/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP CYP1A2 4850/4885CYP3A4 4751/4885CYP2D6 3805/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 CYP1A2 4625/4885CYP3A4 4751/4885CYP2D6 3572/4885
US-20260061042-A1 POLYNUCLEOTIDE COMPOSITIONS AND USES THEREOF SELP, LNPEP, NOP2 CYP1A2 4737/4885CYP3A4 4873/4885CYP2D6 4515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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