Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16114579 | 0.79 | TRPV4 (0.53) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL16305577 | 0.78 | TRIM24 (0.46) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL29953656 | 0.77 | ALDH1A1 (0.51) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL871969 | 0.77 | ALDH1A1 (0.51) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL29118011 | 0.77 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL2600011 | 0.77 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL29366504 | 0.77 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL3687846 | 0.75 | TRIM24 (0.46) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL16096639 | 0.75 | TRIM24 (0.46) | TRIM24TRIM33ALDH1A1HPGDHTT | |
| SCHEMBL16174927 | 0.74 | RXRA (0.41) | ALDH1A1SMN1; SMN2HCRTR2HCRTR1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988169-B | Octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-02-01 | — | — | CN | disclosed |