Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 19/20 | 0.48 |
| ▸ | ITGB8 | P26012 | 18/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 18/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690115 | 1.00 | ITGAV (0.48) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28685987 | 0.87 | ITGAV (0.47) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28699760 | 0.86 | ITGAV (0.46) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28685968 | 0.83 | ITGAV (0.68) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28685964 | 0.83 | ITGAV (0.68) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28709236 | 0.82 | ITGB3 (0.37) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL30898070 | 0.77 | ITGAV (0.43) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL30898216 | 0.76 | ITGAV (0.42) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28699700 | 0.75 | MAPT (0.41) | — | |
| SCHEMBL17642606 | 0.74 | ITGB3 (0.57) | ITGAVITGB6ITGB8ITGB5ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |