Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699688 | 0.89 | ITGAV (0.39) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL28699743 | 0.82 | STS (0.49) | MAPTUSP30BRD4TP53POLB | |
| SCHEMBL28698405 | 0.80 | SMYD3 (0.41) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28709399 | 0.80 | SMYD3 (0.41) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28699817 | 0.78 | LMNA (0.41) | MAPTLMNAALDH1A1 | |
| SCHEMBL28696950 | 0.78 | TP53 (0.42) | MAPTMEN1KMT2AGPR119TP53 | |
| SCHEMBL24036831 | 0.76 | HPGD (0.39) | MAPTTP53POLBALDH1A1L3MBTL1 | |
| SCHEMBL30474591 | 0.76 | MAPT (0.39) | MAPTUSP30MEN1KMT2AGPR119 | |
| SCHEMBL30474534 | 0.75 | USP30 (0.42) | MAPTUSP30MEN1KMT2AGPR119 | |
| SCHEMBL24036983 | 0.74 | MAPT (0.38) | MAPTMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |