Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 17/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 16/20 | 0.46 |
| ▸ | ITGB8 | P26012 | 15/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 15/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 14/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685987 | 0.95 | ITGAV (0.47) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28690115 | 0.86 | ITGAV (0.48) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28690112 | 0.86 | ITGAV (0.48) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28698397 | 0.82 | ITGAV (0.41) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28685968 | 0.80 | ITGAV (0.68) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28685964 | 0.80 | ITGAV (0.68) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28699817 | 0.79 | LMNA (0.41) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL29369724 | 0.76 | LMNA (0.40) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL28699688 | 0.74 | ITGAV (0.39) | ITGAVITGB6ITGB8ITGB5ITGB3 | |
| SCHEMBL20141284 | 0.73 | ITGAV (0.45) | ITGAVITGB6ITGB8ITGB5ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |