Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392263 | 0.80 | DRD4 (0.70) | KDM4EALDH1A1HPGDTRIM24TRIM33 | |
| SCHEMBL23922755 | 0.77 | POLB (0.63) | KDM4EALDH1A1POLBTRIM24TRIM33 | |
| SCHEMBL23922857 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1POLBTRIM24TRIM33 | |
| SCHEMBL3077544 | 0.74 | TRIM24 (0.83) | KDM4EALDH1A1TRIM24TRIM33SMN1; SMN2 | |
| SCHEMBL2561698 | 0.74 | TRIM24 (0.83) | KDM4EALDH1A1TRIM24TRIM33SMN1; SMN2 | |
| SCHEMBL28710553 | 0.73 | HDAC3 (0.57) | KDM4EALDH1A1POLBSMN1; SMN2DRD4 | |
| SCHEMBL27990811 | 0.73 | HRH3 (0.52) | KDM4EALDH1A1POLBTRIM24TRIM33 | |
| SCHEMBL5356967 | 0.72 | ALDH1A1 (0.66) | KDM4EALDH1A1POLBTRIM24TRIM33 | |
| SCHEMBL1540225 | 0.72 | DRD4 (0.54) | KDM4EALDH1A1DRD4MAPT | |
| SCHEMBL28694843 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDTRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-B | 2-phenylimidazo [4,5-B ] pyridin-7-amine derivatives useful as inhibitors of the activity of the mammalian tyrosine kinase ROR1 | 坎塞拉有限公司 | 2021-09-14 | — | — | CN | disclosed |