Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.61 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RAD52 | P43351 | 3/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561698 | 0.84 | TRIM24 (0.83) | ALDH1A1TRIM24TRIM33GAAKDM4E | |
| SCHEMBL3077544 | 0.84 | TRIM24 (0.83) | ALDH1A1TRIM24TRIM33GAAKDM4E | |
| SCHEMBL21411223 | 0.84 | GAA (0.62) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL377522 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TRIM24TRIM33GAAKDM4E | |
| SCHEMBL28137119 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TRIM24TRIM33GAAMAPT | |
| SCHEMBL10900857 | 0.81 | KDM4E (0.67) | ALDH1A1TRIM24TRIM33GAAKDM4E | |
| SCHEMBL14851771 | 0.81 | PIM1 (0.50) | ALDH1A1TRIM24TRIM33GAAMAPT | |
| SCHEMBL29946558 | 0.80 | CHRNA7 (0.57) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29126309 | 0.80 | CHRNA7 (0.57) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL23922764 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900237-B2 | Sulfonamide compounds as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | claimed |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | Celera Corporation | 2003-08-21 | — | — | US | claimed |
| US-20220396583-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2022-12-15 | — | — | US | disclosed |
| EP-3774736-B1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | NEUROPORE THERAPIES INC (US) | 2022-11-16 | — | — | EP | disclosed |
| US-11345713-B2 | Compounds as modulators of TLR2 signaling | NEUROPORE THERAPIES, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| CN-108366979-B | Compounds and pharmaceutical compositions relating to ubiquitination-proteasome system | 博蔚医药生物科技股份有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-109563092-B | 2-phenylimidazo [4,5-B ] pyridin-7-amine derivatives useful as inhibitors of the activity of the mammalian tyrosine kinase ROR1 | 坎塞拉有限公司 | 2021-09-14 | — | — | CN | disclosed |
| US-11084786-B2 | Compounds and pharmaceutical composition associated with ubiquitination-proteasome system | CALGENT BIOTECHNOLOGY CO., LTD. (TW) | 2021-08-10 | — | — | US | disclosed |
| EP-3774736-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | Neuropore Therapies, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20210024539-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2021-01-28 | — | — | US | disclosed |
| US-20200385344-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITION ASSOCIATED WITH UBIQUITINATION-PROTEASOME SYSTEM | CALGENT BIOTECHNOLOGY CO., LTD. (TW) | 2020-12-10 | — | — | US | disclosed |
| US-7247756-B2 | 1,4-disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2007-07-24 | — | — | US | disclosed |
| US-6900237-B2 | Sulfonamide compounds as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-6753429-B2 | FOR USE AS INSECTICIDES AGAINST A VARIETY OF INSECTS, INCLUDING LARVAE, SUCH AS TOBACCO BUDWORM | FMC CORPORATION | 2004-06-22 | — | — | US | disclosed |
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2003-11-06 | — | — | US | disclosed |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | Celera Corporation | 2003-08-21 | — | — | US | disclosed |
| EP-1334083-A2 | 1,4-DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2003024923-A1 | SULFONAMIDE COMPOUNDS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-03-27 | — | — | WO | disclosed |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2002-12-05 | — | — | US | disclosed |
| WO-2002017712-A2 | DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | ALDH1A1 65/4885TRIM24 4075/4885TRIM33 3316/4885 |
| US-11345713-B2 | Compounds as modulators of TLR2 signaling | TLR2, TLR4, TLR3 | ALDH1A1 4464/4885TRIM24 1887/4885TRIM33 3127/4885 |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | PRSS1, PRSS3, SPINT2 | ALDH1A1 2068/4885TRIM24 4159/4885TRIM33 2680/4885 |
| US-11084786-B2 | Compounds and pharmaceutical composition associated with ubiquitination-proteasome system | PSMC1, PSME3, PSMB1 | ALDH1A1 2933/4885TRIM24 319/4885TRIM33 138/4885 |
| US-20200385344-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITION ASSOCIATED WITH UBIQUITINATION-PROTEASOME SYSTEM | PSMC1, PSME3, PSMB1 | ALDH1A1 2933/4885TRIM24 319/4885TRIM33 138/4885 |
| US-20220396583-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | TLR2, TLR4, TLR3 | ALDH1A1 4464/4885TRIM24 1887/4885TRIM33 3127/4885 |
| US-20210024539-A1 | COMPOUNDS AS MODULATORS OF TLR2 SIGNALING | TLR2, TLR4, TLR3 | ALDH1A1 4464/4885TRIM24 1887/4885TRIM33 3127/4885 |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | ALDH1A1 65/4885TRIM24 4075/4885TRIM33 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.