SCHEMBL2869218

SCHEMBL2869218

Nc1cccc2nc3c4ccccc4c4ccccc4c3nc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
HPGD P15428 6/20 0.45
HSD17B10 Q99714 6/20 0.45
TSHR P16473 3/20 0.45
CYP3A4 P08684 2/20 0.45
KEAP1 Q14145 1/20 0.45
CYP1A2 P05177 1/20 0.44
KDM4E B2RXH2 6/20 0.44
GAA P10253 4/20 0.44
RAB9A P51151 4/20 0.44
GLA P06280 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 2/20 0.44
NPC1 O15118 1/20 0.44
PTBP1 P26599 1/20 0.44
RCE1 Q9Y256 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2293195 0.83 MAPT (0.56) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL31355397 0.83 MAPT (0.52) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL28042624 0.79 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL18805402 0.78 MYC (0.52) ALDH1A1HPGDHSD17B10TSHRKDM4E
SCHEMBL732274 0.78 MAPT (0.56) ALDH1A1HPGDHSD17B10TSHRKDM4E
SCHEMBL29581869 0.78 MAPT (0.56) ALDH1A1HPGDHSD17B10TSHRKDM4E
SCHEMBL762952 0.76 ACHE (0.72) ALDH1A1HPGDTSHRCYP1A2KDM4E
SCHEMBL12578240 0.76 RAB9A (0.49) ALDH1A1CYP1A2GAARAB9AKMT2A
SCHEMBL11057014 0.76 CYP1A2 (0.68) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL10603701 0.75 MYC (0.54) ALDH1A1HPGDHSD17B10TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1713101-B1 ELECTRODE FOR ENERGY STORAGE DEVICE AND PROCESS FOR PRODUCING THE SAME UNIV YAMAGUCHI (JP) 2012-10-31 EP disclosed
EP-1713101-B1 ELECTRODE FOR ENERGY STORAGE DEVICE AND PROCESS FOR PRODUCING THE SAME UNIV YAMAGUCHI (JP) 2012-10-31 EP disclosed
US-7803898-B2 Aminoquinoxaline compound, polyaminoquinoxaline compound, and use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-28 US disclosed
US-7803898-B2 Aminoquinoxaline compound, polyaminoquinoxaline compound, and use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-28 US disclosed
US-7803898-B2 Aminoquinoxaline compound, polyaminoquinoxaline compound, and use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-28 US disclosed
US-7799894-B2 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2010-09-21 US disclosed
US-7799894-B2 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2010-09-21 US disclosed
US-7799894-B2 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2010-09-21 US disclosed
US-20090030176-A1 Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-29 US disclosed
US-20090030176-A1 Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-29 US disclosed
US-20090030176-A1 Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-29 US disclosed
US-20070120112-A1 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2007-05-31 US disclosed
US-20070120112-A1 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2007-05-31 US disclosed
US-20070120112-A1 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2007-05-31 US disclosed
EP-1713101-A1 ELECTRODE FOR ENERGY STORAGE DEVICE AND PROCESS FOR PRODUCING THE SAME Yamaguchi University (JP) 2006-10-18 EP disclosed
EP-1705178-A1 AMINOQUINOXALINE COMPOUND, POLYAMINOQUINOXALINE COMPOUND, AND USE THEREOF Nissan Chemical Industries, Ltd. (JP) 2006-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030176-A1 Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof PAM, CYC1, QPCT ALDH1A1 2049/4885HPGD 984/4885HSD17B10 1868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.