Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429079 | 1.00 | CYP11B1 (0.46) | CYP11B1KCNH2AOC3CYP19A1CYP11B2 | |
| SCHEMBL29429075 | 1.00 | CYP11B1 (0.46) | CYP11B1KCNH2AOC3CYP19A1CYP11B2 | |
| SCHEMBL29429090 | 0.87 | HTR6 (0.49) | HTR6KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL29429027 | 0.87 | HTR6 (0.49) | HTR6KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL28684397 | 0.87 | HTR6 (0.49) | HTR6KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL29385594 | 0.82 | KCNH2 (0.41) | CYP11B1KCNH2AOC3CYP19A1CYP11B2 | |
| SCHEMBL29386463 | 0.82 | KCNH2 (0.41) | CYP11B1KCNH2AOC3CYP19A1CYP11B2 | |
| SCHEMBL28681075 | 0.82 | KCNH2 (0.41) | CYP11B1KCNH2AOC3CYP19A1CYP11B2 | |
| SCHEMBL9507245 | 0.80 | AOC3 (0.63) | CYP11B1KCNH2AOC3CYP19A1CYP11B2 | |
| SCHEMBL29429021 | 0.80 | HTR6 (0.43) | HTR6KDM4ENPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |