Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286991 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1MAPK1HIF1AKMT2AAGTR1 | |
| SCHEMBL287785 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1HIF1AKMT2AAGTR1 | |
| SCHEMBL287667 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MAPK1HIF1AKMT2AL3MBTL1 | |
| SCHEMBL287282 | 0.71 | TDP1 (0.43) | ALDH1A1MAPK1HIF1AKMT2AL3MBTL1 | |
| SCHEMBL660547 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MAPK1HIF1AKMT2AAGTR1 | |
| SCHEMBL287683 | 0.66 | NPC1 (0.39) | ALDH1A1KMT2AMEN1KDM4ECYP1A2 | |
| SCHEMBL31114507 | 0.64 | ALDH1A1 (0.62) | ALDH1A1MAPK1HIF1AKMT2AAGTR1 | |
| SCHEMBL6227326 | 0.64 | GLA (0.48) | ALDH1A1MAPK1HIF1AKMT2AAGTR1 | |
| Bromide SCHEMBL1194556 | 0.63 | GLA (0.50) | ALDH1A1MAPK1HIF1AKMT2AAGTR1 | |
| SCHEMBL6941866 | 0.63 | TSHR (0.53) | ALDH1A1MAPK1KMT2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |