Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286951 | 0.80 | ALDH1A1 (0.37) | KMT2AL3MBTL1AGTR1ALDH1A1POLB | |
| SCHEMBL287585 | 0.79 | NPSR1 (0.46) | SMN1; SMN2KMT2AHPGDALDH1A1RAB9A | |
| SCHEMBL287807 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2KMT2AHPGDALDH1A1RAB9A | |
| SCHEMBL286991 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AL3MBTL1AGTR1HPGD | |
| SCHEMBL287282 | 0.74 | TDP1 (0.43) | SMN1; SMN2KMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL6908873 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AL3MBTL1AGTR1TMEM97 | |
| Bromide SCHEMBL1194178 | 0.70 | GLA (0.46) | SMN1; SMN2KMT2AL3MBTL1TMEM97SIGMAR1 | |
| Bromide SCHEMBL6909971 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AL3MBTL1AGTR1TMEM97 | |
| SCHEMBL287667 | 0.69 | ALDH1A1 (0.32) | SMN1; SMN2KMT2AL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL13100724 | 0.65 | HPGD (0.74) | SMN1; SMN2KMT2AHPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |