Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452764 | 0.90 | KMT2A (0.48) | HIF1AEPAS1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL22453772 | 0.89 | MAPT (0.48) | HIF1AEPAS1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL22452498 | 0.88 | HIF1A (0.60) | HIF1AEPAS1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL31555348 | 0.88 | HIF1A (0.60) | HIF1AEPAS1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL22452725 | 0.87 | MEN1 (0.46) | HIF1AEPAS1ALDH1A1KDM4EMEN1 | |
| SCHEMBL22453523 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KDM4EEPHX2FABP4MEN1 | |
| SCHEMBL22452983 | 0.85 | MEN1 (0.48) | HIF1AEPAS1ALDH1A1KDM4EMEN1 | |
| SCHEMBL22453248 | 0.84 | DHODH (0.49) | HIF1AEPAS1ALDH1A1EPHX2MEN1 | |
| SCHEMBL28695220 | 0.84 | EPHX2 (0.43) | ALDH1A1EPHX2MEN1KMT2AGAA | |
| SCHEMBL22453247 | 0.83 | EPHX2 (0.65) | HIF1AEPAS1ALDH1A1KDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |