Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 6/20 | 0.46 |
| ▸ | MMP12 | P39900 | 6/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886826 | 0.93 | MMP2 (0.45) | RAB9ANPC1KMT2AMMP2MMP12 | |
| SCHEMBL29696029 | 0.92 | MMP2 (0.44) | RAB9ANPC1KMT2AMMP2MMP12 | |
| SCHEMBL1149624 | 0.85 | SMN1; SMN2 (0.49) | RAB9ANPC1KMT2AMMP2MMP12 | |
| SCHEMBL10504857 | 0.84 | RAB9A (0.48) | RAB9ANPC1KMT2AMMP2MMP12 | |
| SCHEMBL1149576 | 0.83 | MMP1 (0.50) | RAB9ANPC1KMT2AMMP2MMP12 | |
| SCHEMBL949403 | 0.81 | SMN1; SMN2 (0.51) | RAB9ANPC1KMT2AMMP2MMP12 | |
| SCHEMBL20660941 | 0.77 | HPGDS (0.52) | RAB9ANPC1KMT2AMAPTATM | |
| SCHEMBL10503868 | 0.76 | HSD17B10 (0.46) | RAB9ANPC1KMT2AMMP2MAPT | |
| SCHEMBL29696139 | 0.76 | MMP2 (0.49) | RAB9ANPC1KMT2AMMP2MMP12 | |
| SCHEMBL2422895 | 0.76 | SRD5A2 (0.46) | RAB9ANPC1KMT2AMMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026068-A | EP2 antagonists | 小野药品工业株式会社 | 2022-02-08 | — | — | CN | disclosed |