Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1946431 | 0.87 | ALDH1A1 (0.52) | KDM4ECYP4A11L3MBTL1ALDH1A1CYP4F2 | |
| SCHEMBL948290 | 0.85 | L3MBTL1 (0.58) | KDM4ENAMPTCYP4A11L3MBTL1ALDH1A1 | |
| SCHEMBL3765456 | 0.83 | KLKB1 (0.53) | KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL25123666 | 0.83 | GBA1 (0.47) | CYP4A11L3MBTL1CYP4F2 | |
| SCHEMBL949478 | 0.82 | HDAC6 (0.46) | KDM4ENAMPTL3MBTL1ALDH1A1KDM1A | |
| SCHEMBL27645962 | 0.80 | L3MBTL1 (0.55) | KDM4EL3MBTL1MGLLALDH1A1 | |
| SCHEMBL19434598 | 0.80 | LMNA (0.42) | L3MBTL1HDAC6 | |
| SCHEMBL15175618 | 0.79 | MAPT (0.47) | KDM4ECYP4A11ALDH1A1CYP4F2 | |
| SCHEMBL7315645 | 0.78 | L3MBTL1 (0.53) | KDM4EL3MBTL1MGLLALDH1A1 | |
| SCHEMBL24842016 | 0.78 | L3MBTL1 (0.45) | KDM4ECYP4A11L3MBTL1ALDH1A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026068-A | EP2 antagonists | 小野药品工业株式会社 | 2022-02-08 | — | — | CN | disclosed |