Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 4/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287518 | 0.71 | ALDH1A1 (0.35) | HPGDKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL287640 | 0.69 | ALDH1A1 (0.31) | HPGDTP53KMT2AALDH1A1MEN1 | |
| SCHEMBL9717051 | 0.67 | MMP13 (0.47) | HPGDMMP13TP53KMT2AALDH1A1 | |
| SCHEMBL5320468 | 0.63 | MMP1 (0.56) | HPGDALOX15HSD17B10CA1CA2 | |
| SCHEMBL11611710 | 0.62 | HSP90AA1 (0.47) | HPGDALOX15HSD17B10KMT2AALDH1A1 | |
| SCHEMBL13545205 | 0.59 | HPGD (0.74) | HPGDALOX15HSD17B10CA1CA2 | |
| SCHEMBL15974169 | 0.59 | KDM4E (0.56) | HPGDALOX15KMT2AALDH1A1MEN1 | |
| SCHEMBL11607270 | 0.59 | RORC (0.50) | CA1CA2LIMK1KMT2AALDH1A1 | |
| SCHEMBL9132638 | 0.58 | HPGD (0.59) | HPGDALOX15HSD17B10LIMK2LIMK1 | |
| SCHEMBL13889650 | 0.58 | KMT2A (0.55) | TP53KMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |