Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | F11 | P03951 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12457977 | 0.85 | DGAT1 (0.49) | DGAT1F11GSK3AGSK3BROCK2 | |
| SCHEMBL21293596 | 0.78 | DGAT1 (0.40) | DGAT1GSK3AGSK3BFFAR1LPL | |
| SCHEMBL5336869 | 0.78 | F11 (0.56) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL23287138 | 0.77 | SMN1; SMN2 (0.43) | DGAT1GSK3AGSK3BPDGFRBKDR | |
| SCHEMBL28507924 | 0.77 | F11 (0.37) | DGAT1F11GSK3AGSK3BROCK2 | |
| SCHEMBL4206551 | 0.77 | DGAT1 (0.49) | DGAT1GSK3AGSK3BROCK2PDGFRB | |
| SCHEMBL28499822 | 0.76 | DGAT1 (0.58) | DGAT1F11ROCK2PDGFRBKDR | |
| SCHEMBL20338099 | 0.76 | FFAR1 (0.43) | DGAT1F11GSK3AGSK3BPDGFRB | |
| SCHEMBL25369384 | 0.75 | LPL (0.41) | DGAT1F11GSK3AGSK3BFFAR1 | |
| SCHEMBL1284703 | 0.74 | LPL (0.44) | DGAT1F11GSK3AGSK3BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |