Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875263 | 0.83 | KDM4E (0.61) | KDM4EMAPTTDP1POLBTSHR | |
| SCHEMBL29556324 | 0.83 | KDM4E (0.61) | KDM4EMAPTTDP1POLBTSHR | |
| Pyrazinoic Acid SCHEMBL22409664 | 0.78 | HCAR2 (0.67) | KDM4EMAPTTSHRHCAR2NAPRT | |
| SCHEMBL8345410 | 0.76 | CES2 (0.50) | KDM4EMAPTTDP1POLBTSHR | |
| SCHEMBL28344838 | 0.73 | TSHR (0.62) | KDM4EMAPTTDP1POLBTSHR | |
| SCHEMBL16328267 | 0.73 | KDM4E (0.53) | KDM4EMAPTTDP1POLBTSHR | |
| SCHEMBL11779790 | 0.70 | KDM4E (0.59) | KDM4EMAPTTDP1POLBTSHR | |
| SCHEMBL9616232 | 0.70 | TSHR (0.49) | KDM4EMAPTTDP1POLBTSHR | |
| SCHEMBL27587983 | 0.69 | TSHR (0.57) | KDM4EMAPTTDP1POLBTSHR | |
| SCHEMBL9563007 | 0.69 | TSHR (0.61) | KDM4EMAPTTDP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144174-A | Methods and compositions for supporting kidney health | 加利福尼亚大学董事会 | 2022-03-04 | — | — | CN | disclosed |