Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556324 | 0.84 | KDM4E (0.61) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL875263 | 0.84 | KDM4E (0.61) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL28344838 | 0.78 | TSHR (0.62) | TSHRADORA3MC4RADRA1AMC3R | |
| Pyrazinoic Acid SCHEMBL9616231 | 0.77 | KDM4E (0.69) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL16328267 | 0.74 | KDM4E (0.53) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL8345410 | 0.73 | CES2 (0.50) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL9563007 | 0.73 | TSHR (0.61) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL552688 | 0.72 | KDM4E (0.55) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL11779790 | 0.71 | KDM4E (0.59) | TSHRADORA3MC4RADRA1AMC3R | |
| SCHEMBL28697246 | 0.70 | KDM4E (0.48) | TSHRADORA3MC4RADRA1AMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118937-A | Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules | FINNIGAN MAT GMBH (DE) | 1992-06-02 | — | — | US | disclosed |