Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145 | 0.85 | PARP1 (0.60) | MAPTALDH1A1HPGDACHEPARP1 | |
| SCHEMBL29559082 | 0.85 | PARP1 (0.60) | MAPTALDH1A1HPGDACHEPARP1 | |
| SCHEMBL29410201 | 0.85 | PARP1 (0.60) | MAPTALDH1A1HPGDACHEPARP1 | |
| Acridine SCHEMBL28191835 | 0.83 | ALDH1A1 (0.62) | MAPTALDH1A1HPGDACHEGLA | |
| Carbazole SCHEMBL28956846 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDACHEPARP1 | |
| SCHEMBL28982242 | 0.83 | PARP1 (0.58) | MAPTALDH1A1HPGDACHEPARP1 | |
| Hydrochloric Acid SCHEMBL2770160 | 0.83 | PARP1 (0.58) | MAPTALDH1A1HPGDACHEPARP1 | |
| Carbazole SCHEMBL143086 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDACHEPARP1 | |
| Formaldehyde SCHEMBL28560487 | 0.80 | PARP1 (0.59) | MAPTALDH1A1HPGDACHEPARP1 | |
| SCHEMBL2422471 | 0.78 | POLB (0.58) | MAPTALDH1A1HPGDACHEGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113980002-B | Azacyclocarbazole compound and application thereof | 广东工业大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-113980002-A | Azacyclocarbazole compound and application thereof | 广东工业大学 | 2022-01-28 | — | — | CN | disclosed |