Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28697863 | 0.98 | KDM4E (0.36) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1655533 | 0.86 | TRPV6 (0.42) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29909305 | 0.86 | TRPV6 (0.42) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL6853901 | 0.78 | HDAC2 (0.43) | HDAC2JAK2JAK1TYK2JAK3 | |
| SCHEMBL25702645 | 0.77 | KDM4E (0.54) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL6665053 | 0.77 | HDAC2 (0.41) | HDAC2 | |
| SCHEMBL28697825 | 0.76 | DGAT1 (0.43) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29368860 | 0.76 | PSMB5 (0.36) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL21819234 | 0.76 | PSMB5 (0.36) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL21819236 | 0.76 | PSMB5 (0.36) | KDM4EGLAHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |