Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698330 | 0.81 | CSNK2A1 (0.45) | CYP2A6MAPTL3MBTL1RAB9ALMNA | |
| SCHEMBL3892797 | 0.79 | ALDH1A1 (0.49) | MAPTL3MBTL1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL14060017 | 0.78 | ALDH1A1 (0.40) | CNR2CYP2A6MAPTL3MBTL1RAB9A | |
| SCHEMBL28698347 | 0.77 | SMN1; SMN2 (0.47) | MAPTL3MBTL1RAB9ALMNAMAPK1 | |
| SCHEMBL4027686 | 0.77 | CHKA (0.57) | MAPTL3MBTL1RAB9ALMNAMAPK1 | |
| SCHEMBL31013493 | 0.76 | ALDH1A1 (0.62) | MAPTL3MBTL1RAB9ALMNAMAPK1 | |
| Fluoride SCHEMBL27569609 | 0.75 | CHKA (0.56) | MAPTL3MBTL1RAB9ALMNAMAPK1 | |
| SCHEMBL17120712 | 0.75 | ESR2 (0.53) | CNR2MAPTL3MBTL1RAB9ALMNA | |
| SCHEMBL22816853 | 0.75 | KIF11 (0.45) | MAPTL3MBTL1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL28713547 | 0.75 | S1PR1 (0.66) | MAPTL3MBTL1RAB9ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206843-A | Compounds for modulating proprotein convertase subtilisin/Kexin type 9(PCSK9) | SRX心脏有限责任公司 | 2022-03-18 | — | — | CN | disclosed |