Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426595 | 0.80 | HPGD (0.54) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL16727172 | 0.78 | MAPT (0.53) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL30228205 | 0.78 | MEN1 (0.69) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL28698328 | 0.77 | CNR2 (0.55) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL8264511 | 0.76 | MAPT (0.68) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL22818552 | 0.74 | ADRB1 (0.66) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL8390975 | 0.74 | ADRB1 (0.66) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL28698330 | 0.72 | CSNK2A1 (0.45) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL27781528 | 0.72 | PLA2G7 (0.52) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL27781527 | 0.72 | PLA2G7 (0.52) | SMN1; SMN2MEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206843-A | Compounds for modulating proprotein convertase subtilisin/Kexin type 9(PCSK9) | SRX心脏有限责任公司 | 2022-03-18 | — | — | CN | disclosed |