Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | S100B | P04271 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816853 | 0.83 | KIF11 (0.45) | AVPR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28698328 | 0.81 | CNR2 (0.55) | CYP2A6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18411537 | 0.79 | PDK2 (0.46) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7715055 | 0.77 | ADRB1 (0.66) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL28713548 | 0.76 | HTR7 (0.55) | LMNASMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL4027686 | 0.75 | CHKA (0.57) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL9830834 | 0.75 | ADRB1 (0.68) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL13425581 | 0.74 | KIF11 (0.45) | LMNAMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL30228205 | 0.74 | MEN1 (0.69) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| Fluoride SCHEMBL27569609 | 0.74 | CHKA (0.56) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206843-A | Compounds for modulating proprotein convertase subtilisin/Kexin type 9(PCSK9) | SRX心脏有限责任公司 | 2022-03-18 | — | — | CN | disclosed |