Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364217 | 0.77 | L3MBTL1 (0.62) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| SCHEMBL250301 | 0.76 | LMNA (0.65) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| SCHEMBL28459061 | 0.76 | LMNA (0.69) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| Acetic Acid SCHEMBL8159401 | 0.75 | PDE10A (0.60) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| Hydrochloric Acid SCHEMBL2563239 | 0.75 | LMNA (0.63) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| Butanedione SCHEMBL5530736 | 0.75 | LMNA (0.63) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| SCHEMBL3453971 | 0.74 | KDM4E (0.64) | MAPTLMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL8871046 | 0.74 | MAPT (0.67) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| SCHEMBL10385035 | 0.73 | LMNA (0.72) | MAPTLMNAL3MBTL1HDAC6METAP2 | |
| SCHEMBL2839930 | 0.73 | LMNA (0.60) | MAPTLMNAL3MBTL1HDAC6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156762-B | Aggregation-induced emission material containing quinoline and coumarin functional groups and preparation method thereof | 山西大学 | 2021-12-31 | — | — | CN | disclosed |