Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | METAP2 | P50579 | 1/20 | 0.63 |
| ▸ | METAP1 | P53582 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250301 | 0.98 | LMNA (0.65) | LMNAMETAP2METAP1HDAC6KDM4E | |
| Hydrochloric Acid SCHEMBL2563239 | 0.97 | LMNA (0.63) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL19733333 | 0.86 | LMNA (0.51) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL28459061 | 0.84 | LMNA (0.69) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL2839930 | 0.84 | LMNA (0.60) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL3415803 | 0.83 | LMNA (0.71) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL7364217 | 0.82 | L3MBTL1 (0.62) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL3454629 | 0.81 | LMNA (0.61) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL111242 | 0.81 | LMNA (0.65) | LMNAMETAP2METAP1HDAC6KDM4E | |
| SCHEMBL10356985 | 0.81 | LMNA (0.65) | LMNAMETAP2METAP1HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264960-B2 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-20050026260-A1 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | RESNICK SOL M (US) | 2005-02-03 | — | — | US | disclosed |