Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459044 | 0.82 | CES2 (0.48) | MLYCDLMNATRPM8CLK1DYRK1A | |
| SCHEMBL24664552 | 0.79 | MLYCD (0.44) | MLYCDLMNATRPM8CLK1DYRK1A | |
| SCHEMBL1002689 | 0.79 | MLYCD (0.47) | MLYCDLMNATRPM8CLK1DYRK1A | |
| SCHEMBL3651911 | 0.77 | MLYCD (0.47) | MLYCDTRPM8CLK1DYRK1ADYRK1B | |
| SCHEMBL23708187 | 0.76 | ERN1 (0.48) | MLYCDERN1MAOB | |
| SCHEMBL2883042 | 0.76 | CES2 (0.52) | MLYCDERN1LMNATRPM8CLK1 | |
| SCHEMBL31346688 | 0.75 | ALOX5 (0.51) | MLYCDERN1LMNAMAPK1HTT | |
| SCHEMBL26709446 | 0.75 | LMNA (0.42) | MLYCDLMNACLK1DYRK1ADYRK1B | |
| SCHEMBL14059749 | 0.75 | KDM4E (0.52) | ERN1LMNANFKB1NFKB2RELA | |
| SCHEMBL24664554 | 0.74 | MLYCD (0.40) | MLYCDLMNATRPM8CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085220-B | Substituted morpholine-4-carboxylic acid ester derivatives, compositions and pharmaceutical uses thereof | 上海海雁医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-114085220-A | Substituted morpholine-4-carboxylic ester derivatives, their compositions and their medical use | 上海海雁医药科技有限公司 | 2022-02-25 | — | — | CN | disclosed |