Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364565 | 0.83 | MEN1 (0.44) | MTORRAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL4367416 | 0.82 | ALDH1A1 (0.43) | RAB9ASMN1; SMN2L3MBTL1MEN1NPC1 | |
| SCHEMBL28715025 | 0.81 | MAPT (0.38) | AKT1KCNN4HDAC3HDAC1HDAC2 | |
| SCHEMBL28708777 | 0.81 | AKT1 (0.40) | AKT1KCNN4HDAC3HDAC1HDAC2 | |
| SCHEMBL28699987 | 0.80 | KCNN4 (0.40) | AKT1KCNN4HDAC3HDAC1HDAC2 | |
| SCHEMBL15739513 | 0.80 | MAPT (0.41) | HDAC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4370578 | 0.79 | FADS1 (0.41) | MTORHDAC2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4366472 | 0.79 | FABP4 (0.42) | RAB9ASMN1; SMN2L3MBTL1MEN1NPC1 | |
| SCHEMBL7659114 | 0.77 | MTOR (0.50) | MTORSMN1; SMN2NAPRTHSD17B10MEN1 | |
| SCHEMBL4367466 | 0.76 | GPR119 (0.40) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021140-A1 | COMPOUND FOR DEGRADING TARGET PROTEIN | 海南先声再明医药股份有限公司 | 2025-01-30 | — | — | WO | disclosed |
| CN-115960094-A | Preparation and application of aromatic ring substituted methylamine derivative | 上海璎黎药业有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-114195676-B | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114195676-A | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-03-18 | — | — | CN | disclosed |