Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699987 | 0.83 | KCNN4 (0.40) | LMNACA12CA1CA7CA14 | |
| SCHEMBL29257492 | 0.81 | PDK1 (0.41) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL28699685 | 0.76 | AKT1 (0.38) | PDK1PDK2PDK3PDK4CA12 | |
| SCHEMBL28715025 | 0.75 | MAPT (0.38) | LMNACA12CA1CA7CA14 | |
| SCHEMBL28708777 | 0.75 | AKT1 (0.40) | PDK1PDK2PDK3PDK4CA12 | |
| SCHEMBL4367466 | 0.71 | GPR119 (0.40) | L3MBTL1 | |
| SCHEMBL14697845 | 0.68 | NFKB1 (0.40) | LMNAAKT1HDAC3HDAC1HDAC2 | |
| SCHEMBL7659114 | 0.68 | MTOR (0.50) | PDK1PDK2PDK3PDK4MLYCD | |
| SCHEMBL28699974 | 0.68 | AKT1 (0.46) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL12311224 | 0.68 | GBA1 (0.44) | PDK2HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195676-B | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114195676-A | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-03-18 | — | — | CN | disclosed |