Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474596 | 0.92 | GPR119 (0.39) | MAPTUSP30MEN1KMT2AJAK2 | |
| SCHEMBL30474554 | 0.81 | KCNH2 (0.38) | MEN1KMT2A | |
| SCHEMBL30474577 | 0.80 | SLC6A2 (0.35) | MAPT | |
| SCHEMBL30474534 | 0.80 | USP30 (0.42) | MAPTUSP30MEN1KMT2AGPR119 | |
| SCHEMBL30474506 | 0.78 | TP53 (0.43) | MAPTUSP30MEN1KMT2AGPR119 | |
| SCHEMBL28699700 | 0.76 | MAPT (0.41) | MAPTUSP30MEN1KMT2AGPR119 | |
| SCHEMBL28699698 | 0.74 | PTPN2 (0.51) | MAPTUSP30MEN1KMT2AGPR119 | |
| SCHEMBL7928638 | 0.66 | KDM4E (0.45) | MAPTMEN1KMT2AGPR119IDO1 | |
| SCHEMBL28709403 | 0.65 | SMN1; SMN2 (0.43) | MAPTMEN1KMT2ALMNA | |
| SCHEMBL16140868 | 0.65 | L3MBTL1 (0.48) | MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-B | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2023-04-18 | — | — | CN | disclosed |