Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 7/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16394573 | 0.92 | GPR119 (0.52) | GPR119KDM1AHDAC8HDAC6KDM4E | |
| SCHEMBL16394574 | 0.92 | GPR119 (0.52) | GPR119KDM1AHDAC8HDAC6KDM4E | |
| SCHEMBL16394326 | 0.83 | FPR2 (0.44) | GPR119KDM1AHDAC8HDAC6KDM4E | |
| SCHEMBL16407913 | 0.83 | FPR2 (0.44) | GPR119KDM1AHDAC8HDAC6KDM4E | |
| SCHEMBL16394325 | 0.83 | FPR2 (0.44) | GPR119KDM1AHDAC8HDAC6KDM4E | |
| SCHEMBL18845512 | 0.82 | KDM1A (0.43) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL28767601 | 0.82 | ACHE (0.39) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL17002642 | 0.81 | KDM1A (0.45) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL17002639 | 0.81 | KDM1A (0.45) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL24890923 | 0.79 | KDM1A (0.48) | KDM1AHDAC8HDAC6EZH2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266345-B | (hetero) arylcyclopropylamine compounds as LSD1 inhibitors | 奥瑞泽恩基因组学股份有限公司 | 2021-08-17 | — | — | CN | disclosed |